Improved multilineage human hematopoietic reconstitution and function in NSGS mice
Fig 2
Differential myeloid and NK differentiation in NSGS compared to NSG.
A) Representative FACS analysis of BM from UCB CD34+ engrafted mice co-stained with CD11b and CD16 antibodies at 15 weeks of engraftment. Average and standard deviation of a cohort of mice stained and analyzed as in A and represented as percentage of B) CD11b+ cells or C) CD45+ cells. D) Average percentage of CD56+ NK cells in BM of the same engrafted mice. Asterisks indicate p value less than 0.05 by Student’s T Test.