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Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer’s disease and normalized by treatment with anti-diabetic agents

Fig 5

IRSP-associated markers in microvascular enriched isolates from the parahippocampal gyrus.

Values represent relative log fold change in persons with AD relative to controls and log fold change in persons with AD and T2D who had been treated with anti-diabetes agents. * = p<0.05 after FDR correction; # = p<0.05 without FDR correction; ✦ = p<0.05 AD-No Treatment vs. AD-T2D Treatment.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0206547.g005