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Pre-clinical assay of the tissue integration and mechanical adhesion of several types of cyanoacrylate adhesives in the fixation of lightweight polypropylene meshes for abdominal hernia repair

Fig 5

Morphological studies of the implanted meshes at 180 days.

Light microscopy images of the large pore polypropylene mesh, fixed with stitches or with the different cyanoacrylates (Glubran 2, SafetySeal, Ifabond and Evobond), 180 days after implantation. Left images: Masson’s trichrome staining panoramic images of the implant meshes (100x magnification). Right images: sirius red staining images, where it is possible to appreciate collagen expression in the different implanted groups after 180 days. Type I collagen was the main collagen seen at this study time (100x magnification). Type I collagen is seen in red, and type III collagen is seen in yellow-green. (PP: polypropylene mesh filament; TA: tissue adhesive).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0206515.g005