Affinity, potency, efficacy, and selectivity of neurokinin A analogs at human recombinant NK2 and NK1 receptors
Fig 9
Representative curves showing displacement of [3H]-septide binding to human recombinant NK1 receptors by substance P, NKA, septide, [Lys5,MeLeu9,Nle10]-NKA(4–10), [Lys5,MeLeu9]-NKA(4–10) and [Arg5,MeLeu9]-NKA(4–10).
Displacement curves were fitted using a one-site model. Values are means ± SD from a representative experiment performed in duplicate.