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Affinity, potency, efficacy, and selectivity of neurokinin A analogs at human recombinant NK2 and NK1 receptors

Fig 4

Concentration-response curves for individual test compounds on intracellular calcium levels using human cloned NK2 and NK1 receptors.

Data are expressed as % of maximal response to 30 nM NKA (for NK2 receptors) or 30 nM substance P (for NK1 receptors). Triangles are NK2 receptors; circles are NK1 receptors. Each data point is the mean ± SD of data from an individual experiment performed in duplicate.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0205894.g004