A control mechanism for intra-mural peri-arterial drainage via astrocytes: How neuronal activity could improve waste clearance from the brain
Fig 4
Comparison of IPAD velocities in an arteriole for varying numbers of astrocytes acting on the wall and strength of the valve-like mechanism.
An astrocyte end-foot is modelled with a width of 10 μm and gap between astrocytes 1 μm. Length has a negative effect on IPAD whilst the number of astrocytes acting on the arteriole simultaneously has a positive effect. k = 1 × 10−3 μm2, arteriole length l = 309 μm, number of astrocytes: 10 (black), 5 (white), 2 (gray), 1 (dotted).