A control mechanism for intra-mural peri-arterial drainage via astrocytes: How neuronal activity could improve waste clearance from the brain
Fig 2
Effect of the release of K+ and Glu into the synaptic space of a neuron and an astrocyte process.
Glu here refers to the ratio of bound/unbound Glu receptors (dimensionless). The arterial radius is modelled using a system of ODE [18] with corrections to the equations listed in [24]. The model shows dilatation of the artery of 20%. This figure only shows the input (a) and result (b) of the functional hyperaemia model. We refer the reader to the original and reimplementation publications for the full details of the chemical cascade implemented in the model and the source code.