Design and evaluation of selective butyrylcholinesterase inhibitors based on Cinchona alkaloid scaffold
Fig 6
CD-(pBr) (stick model) and CN-(pBr) (yellow stick model) in the active site of AChE obtained by ONIOM calculations.
The hydroxyl group hydrogen bond is marked with a green line and the values are given in Å. Only amino acids in the vicinity (up to 4 Å) of the compounds are displayed. Hydrogen atoms of amino acid are omitted for clarity.