Dynamic and tissue-specific proteolytic processing of chemerin in obese mice
Fig 7
Adiponectin levels in plasma and adipose tissue extracts of mice fed a low-fat or high-fat diet.
Adiponectin in plasma (A), epididymal fat extracts (B), and brown fat extracts (C) of 12 weeks old mice fed with either a LF (designated with a blue circle) or HF (designated with a red square) diet, and 26 weeks old mice fed with either a LF (designated with a blue triangle) or HF (designated with a red triangle) diet were determined with the adiponectin ELISA. Horizontal lines show the mean ± SEM. (n = 4 for A, n = 5–11 for B, and n = 10–14 for C). Multigroup comparison was by ANOVA followed by Kruskal-Wallis analysis. *: p<0.05; **: p<0.01; *** p<0.001 ****: p<0.0001. (D) relationship between adiponectin and total chemerin in epididymal fat extracts (n = 30). The Pearson correlation coefficient was calculated with a two-tailed p value.