Nanoplasmonic pillars engineered for single exosome detection
Fig 5
(A) Spatially averaged data from three individual nanopillars (0.36 μm2) in blue, red, and black, respectively (background subtracted). (B) LSPRi of 20 x 20 nanosensor array highlighting a subsampled area for individual nanostructure measurements. Scale bar 1 μm. (C) Zoomed in view of the single nanosensor measurement area. 1 × 105 exosomes/ml were introduced at t ~ 1200 sec. The sharp jumps and stochastic nature of the detection events are consistent with single exosome detection.