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Intrinsic proteotoxic stress levels vary and act as a predictive marker for sensitivity of cancer cells to Hsp90 inhibition

Fig 3

Viability analysis of SK-BR-3 and T-47D cells.

SK-BR-3 and T-47D cells were cultivated in physiological conditions (37 °C) and elevated temperature (39 °C) after 72 h NVP-AUY922 treatment. Viability analysis was performed in 3 biological replicates. (* p = 0,0377; **p = 0,0023).

Fig 3

doi: https://doi.org/10.1371/journal.pone.0202758.g003