Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine in healthy volunteers in a randomized, controlled clinical trial
Fig 2
Visual analog scale pain scores after DNA/placebo and VSV-Gag/placebo vaccine delivery.
Participants rated their pain between 0 (no pain) and 10 (worst possible pain). The graph shows the mean and 95% CI of VAS scores at 3 timepoints indicating minutes after injection, shown by injection visits and treatment arms. The 95% CI was estimated using t-distribution with n-1 degrees of freedom. Pain scores were maximal at 0 minutes after electroporation, and significantly lower in T4 compared to other treatment arms at that timepoint.