Pancreatic cancer survival analysis defines a signature that predicts outcome
Fig 2
Validation of survival DEG list.
(A) Volcano plot highlighting genes associated with survival from TCGA dataset. (B) Bar graph depicting the top 26 enriched pathways based on Reactome pathways analysis of the 602 up-regulated gene from the 707 DEG list. (C) Scatter plot of log fold change of differentially expressed genes vs delta beta of differentially methylated genes between Survival- and Survival+ samples. False indicates methylation status opposite of predicted for gene expression change (total of 31 genes). True indicates concordance between methylation status and gene expression change (total of 676 genes). (D) Bar chart showing percentage overlap of Pancreatic Cancer DEG list with indicated published signatures.