Differential effects of angiotensin II type I receptor blockers on reducing intraocular pressure and TGFβ signaling in the mouse retina
Fig 2
Tissue distribution of ARBs after delivery via chow.
Mice (n = 11) were fed chow containing losartan, irbesartan or telmisartan available ad libidum. After 3 days, mice were sacrificed and eyes, brain, and plasma were collected for LC/MS analysis of drug concentrations. Irbesartan, telmisartan, losartan and EXP 3174 were detected in eyes, brain, and plasma samples. Solid symbols represent data from individual mice, with mean indicated as horizontal line for each group. Data are visualized on logarithmic scale.