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BioNet: A Python interface to NEURON for modeling large-scale networks

Fig 6

Computing extracellular potential.

(A) Schematic of the compartmental model of a cell in relationship to the recording electrode. The calculation of the extracellular potential involves computing the transfer resistances Rmn between each n-th dendritic segment and m-th recording site on the electrode. (B) Extracellular spike “signatures” of individual cells recorded on the mesh electrode (black dots), using two single-cell models from the layer 4 network model as examples: PV2 (left) and Nr5a1 (right). (C) Modeled extracellular recordings with the linear electrode positioned along the axis of the cylinder in the layer 4 model (left). Extracellular potential responses (right) show all simulated data (color map) as well as from six select channels (black traces superimposed on the color map).

Fig 6

doi: https://doi.org/10.1371/journal.pone.0201630.g006