Mathematical modeling of disease dynamics in SDHB- and SDHD-related paraganglioma: Further step in understanding hereditary tumor differences and future therapeutic strategies
Fig 2
Clinical states and transitions in SDHD-mutation carriers.
Only the situation where the pathogenic variant is inherited from the father is considered. Transition probabilies are provided in the Tsdhd matrix. Transition probabilities are represented in a 4–4 matrix (with 4 rows and 4 columns, upper right). Numerical values for steady states and transition probabilities are displayed here and also given in Table 1 and Table 2.