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Amyloidogenic cross-seeding of Tau protein: Transient emergence of structural variants of fibrils

Fig 3

TEM images of G0, G1, G2 and G3 generations of Tau amyloid fibrils.

Red arrowheads indicate morphological variations in the fibrils: paired straight structures formed by K18 and propagated on to G1 and G2 generations of FL Tau fibrils (panels B, E, H), or PHF-like structures formed by K18ΔK280 and propagated on to FL Tau fibrils (panels C, F). Representative images were chosen. Scale bar of 200 nm applies to all micrographs.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0201182.g003