In vitro and in vivo apatinib inhibits vasculogenic mimicry in melanoma MUM-2B cells
Fig 5
A:The traditional endothelial-dependent vessels and VM with CD31-PAS double staining with different concentrations of apatinib in models of melanoma cancer (A a-d: at 200×magnification, A e-h: at 400× magnification, green arrow: structure of VM, red arrow: structure of endothelial-dependent vessels). B:The quantification of microvessel density (MVD) and vasculogenic mimicry density (VMD). *p < 0.05 and **p < 0.01 vs.NS.