Androgen receptor isoforms expression in benign prostatic hyperplasia and primary prostate cancer
Fig 4
Stratification of PCa samples between Gleason grade (≤7(3+4) and ≥7(4+3).
(A) Age at surgery. The group low grade (≤7(3+4) was younger than the high grade group (≥7(4+3) (63 and 68 years, respectively. P = 0.047). (B) AR-FL levels were similar between groups (P = 0.836). (C) AR-V1 levels failed to reach significance (P = 0.060), but seems to be up-regulated in high grade group (≥7(4+3). (D) and (E) AR-V4 and AR-V7rv levels are higher in high grade group (≥7(4+3) (P = 0.004 and P = 0.014). (F) AR-FL/AR-V4 ratio was higher in low grade group (≤7(3+4), P = 0.021). The bars represent the minimum to maximum values.