The gill-associated microbiome is the main source of wood plant polysaccharide hydrolases and secondary metabolite gene clusters in the mangrove shipworm Neoteredo reynei
Fig 4
Gill genome bins contigs for Biosynthetic Gene Clusters (BGCs).
A) Secondary metabolomes. BGCs/contigs detected in Teredinibacter turnerae (T7901 and gills.bin.1), Teredinibacter sp.(gills.bin.4) and on contigs derived from N. reynei gill assembled dataset. Clusters are grouped, and color coded according to the compound class. B) Novel putative trans-AT PKS biosynthetic gene clusters detected on Teredinibacter sp. gills.bin.4 genome and the main predicted catalytic domains of their open reading frames (ORFs). Biosynthetic, transport-related, regulatory, other β-branching-related genes are color coded in dark-blue, light-blue, green, gray and orange respectively. antiSMASH gene clusters abbreviations (not cited on the main text body): PUFA—Polyunsaturated fatty acids; hrslactone–homoserine lactone. Domains keys: thioesterase (TE), aminotransferase (AMT), adenylation (A), ketosynthase (KS), ketoreductase (KR), dehydrogenase (DH), thiolation (T), enoyl-CoA dehydratases (ECH), 2-Nitropropane dioxygenase (2NPD), polyketide synthase cyclase (PKS CY), 4'-phosphopantetheinyl transferase (4PPT). Putative inter-proteins bimodules are present in yellow, PKS-encoded ECH catalytic domains are present in orange.