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Gene expression in the corneal endothelium of Fuchs endothelial corneal dystrophy patients with and without expansion of a trinucleotide repeat in TCF4

Fig 2

Identification of a rare LAMC1 variant in RNA79 (from patient 2011–291).

RNASeq (top panel) and exome sequencing data (bottom panel) from the same individual are shown. The location of a C->T variant which leads to the R490W substitution in the LAMC1 protein is highlighted in both panels. Images were obtained from the Integrative Genomics Viewer.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0200005.g002