Structural definition of hSP-D recognition of Salmonella enterica LPS inner core oligosaccharides reveals alternative binding modes for the same LPS
Fig 3
Structure of the 4,7 closure furanoid derivative (anhydro Kdo) of Kdo following LPS delipidation by mild acid hydrolysis and β-elimination of the Kdo O4 substituent, reported by Shrive and co-workers (PDB ID 4E52, ligand KD5).
Anhydro Kdo is proposed to be a racemic mixture (Auzanneau et al., 1991 [43]) with the 2-oxobutanoic acid side chain at C4 both alpha and beta to the glycosidic bond (at C5). (a) Original Kdo numbering retained. (b) Numbering according to pdb entry 4E52 (alpha) and used for the structure here.