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Non-nutritive sweeteners possess a bacteriostatic effect and alter gut microbiota in mice

Fig 2

Ace K and saccharin show bacteriostatic effects on E. coli in vitro.

Ace K (2.5%, w/v) and saccharin (2.5%, w/v) inhibited (A) E. coli HB101 and (B) E. coli K-12 strains in LB liquid culture, n = 3. All data represent mean ± S.E.M., One-way analysis of variance (ANOVA) with Bonferroni’s test was used for multiple comparisons. ***p <0.001.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0199080.g002