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Glucagon-like peptide 1 receptor (GLP-1R) expression by nerve fibres in inflammatory bowel disease and functional effects in cultured neurons

Fig 3

CGRP and GLP-1R immunostaining in colon and DRG.

CGRP neuronal staining (arrowed) in mucosal sigmoid colon biopsy specimens from control (A), IBD (B and C), magnification x40. Bar chart showing image analysis of CGRP in colonic biopsies (mean ± SEM, Mann Whitney U test) (D). GLP-1R (Abcam antibody, E), and PGP9.5 (F), staining in avulsion injury DRG, magnification x20.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0198024.g003