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Novel isoguanine derivative of unlocked nucleic acid—Investigations of thermodynamics and biological potential of modified thrombin binding aptamer

Fig 5

Anticoagulant activity of TBA variants modified with RNA-iG or UNA-iG (A), RNA-iG and RNA-s4U (B), UNA-iG and UNA-s4U (C).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0197835.g005