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Cell electrofusion based on nanosecond/microsecond pulsed electric fields

Fig 1

Schematic diagram of cell fusion using a sequential nanosecond/microsecond electric field pulse combination.

100-ns-long strong field pulse induced many tiny pores in the cell membrane, particularly in the junction region. After a brief delay, fusion process was followed by a low-field 10-microsecond pulse, which enlarged the pores.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0197167.g001