Improvement of kynurenine aminotransferase-II inhibitors guided by mimicking sulfate esters
Fig 4
Comparative lengths of the structures when fully extended.
Distances measured in the 3D conformer of the compounds, generated from LigPrep at the time of preparation for docking, from the first carbon atom (A) in each compound to the carbon from which the carboxyl branches off (B), the furthest carbon atom (C), or the sulfur atom in the sulfate/sulfonamide groups (D).