Inhibition of sperm motility in male macaques with EP055, a potential non-hormonal male contraceptive
Fig 3
Levels of EP055 in individual Macaca mulatta males after a single i.v. dose.
Each animal was given a low dose of EP055 (75–80 mg/kg). After sperm motility returned to normal, the same animal was given the high dose (125–130 mg/kg). Blue is male 28187, Orange is male 28043, Green is male 25854, Purple is male 28106. (A) Plasma and (C) Semen levels after the low dose of EP055. (B) Plasma and (D) Semen levels after the high dose of EP055.