Cardioprotection of tilianin ameliorates myocardial ischemia-reperfusion injury: Role of the apoptotic signaling pathway
Fig 6
(A): Bcl-2, Bax and GAPDH expression levels in the myocardial tissue of each group. (1: Sham, 2: MIRI, 3: L-tilianin, 4: M-tilianin and 5: H-tilianin) (#P<0.05, ##P<0.01 vs. the Sham group;*P<0.05, **P<0.01 vs. the MIRI group, n = 10). (B): Cleaved-caspase-3, caspase-3 and β-actin expression levels in the myocardial tissue of each group. (1: Sham, 2: MIRI, 3: L-tilianin, 4: M-tilianin and 5: H-tilianin) (#P<0.05, ##P<0.01 vs. the Sham group; **P<0.01 vs. the MIRI group, n = 10). (C): XIAP, HtrA2/Omi, Smac/Diablo and β-actin expression levels in the myocardial tissue of each group. (1: Sham, 2: MIRI, 3: L-tilianin, 4: M-tilianin and 5: H-tilianin) (#P<0.05, ##P<0.01 vs. the Sham group;*P<0.05, **P<0.01 vs. the MIRI group, n = 10). (D): Caspase-7, Caspase-9 and β-actin expression levels in the myocardial tissue of each group. (1: Sham, 2: MIRI, 3: L-tilianin, 4: M-tilianin and 5: H-tilianin) (#P<0.05, ##P<0.01 vs. the Sham group;*P<0.05, **P<0.01 vs. the MIRI group, n = 10).