Macrophage polarization and acceleration of atherosclerotic plaques in a swine model
Fig 5
OCT of atheromatous characteristics and histologic classification based on AHA criteria.
(A) Optical coherence tomography (OCT) images of atheromatous characteristics of the arteries of mini-pigs with induced atherosclerosis from the saline (n = 11), HMGB1 (n = 11), and TNF-α (n = 10) groups. White arrows indicate location of plaques. (B) Histologic classification of plaques from each group according to the American Heart Association (AHA) criteria. Plaque characteristics were categorized into early (type I [blue], II [orange], and III [grey]) and advanced (type IV [yellow]).