DJ-1 based peptide, ND-13, promote functional recovery in mouse model of focal ischemic injury
Fig 4
Effect of ND-13 treatment on functional recovery of DJ-1 KO mice after ET-1 induced focal ischemic injury.
DJ-1 KO mice treated with ND-13 show improvement 2 days after ischemic injury in the elevated bridge test as they spend less time crossing the beam than wild type mice (A, p<0.05). This effect was consistent for at least two weeks following injury. Improvement was also noted in cylinder test 7 days after injury (B). (Data is shown as mean ± SEM).