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Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models

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Apparent in vitro permeability of diastereomers of fosmetpantotenate, PA, and PPA in a blood—Brain barrier permeability model using co-cultured porcine brain endothelial cells and rat astrocytesa.

Table 3

doi: https://doi.org/10.1371/journal.pone.0192028.t003