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Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models

Fig 8

Fosmetpantotenate, PPA, and total PA in mouse brain striatal dialysate.

Single administration of fosmetpantotenate in C57Bl6 mice (700 mg/kg orally or 125 μg intrastriatally).

Fig 8

doi: https://doi.org/10.1371/journal.pone.0192028.g008