Testosterone-induced benign prostatic hyperplasia rat and dog as facile models to assess drugs targeting lower urinary tract symptoms
Fig 2
Effects of silodosin on the micturition parameters in testosterone-induced BPH rats.
Twenty minutes after oral administration of silodosin, distilled water (30 ml/kg) were given orally, and the micturition parameters of BPH rats were measured for the first 2 hours after water load. (A) Micturition frequency, (B) mean voided volume and (C) total voided volume were measured in a metabolic cage. *P < 0.05, **P < 0.01 and ***P < 0.001 versus vehicle control (One-way ANOVA test).