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Changes in liver stiffness measurement using acoustic radiation force impulse elastography after antiviral therapy in patients with chronic hepatitis C

Fig 2

Receiver operating characteristic (ROC) curves using baseline liver stiffness (LS), fibrosis-4 (FIB-4) index, and the aspartate aminotransferase-to-platelet ratio index (APRI), and hepatitis C viral (HCV) load to dichotomize sustained virologic response (SVR) (no versus yes).

According to the ROC analysis, the areas under curves were 0.624 (95% confidence interval, 0.514–0.733), 0.655 (0.560–0.751), 0.594 (0.496–0.692), and 0.618 (0.520–0.716) for baseline LS (A), the FIB-4 index (B), APRI (C), and HCV viral load (D), respectively, to dichotomize SVR (no versus yes). The comparison of the AUCs was not significant between the FIB-4 index and LS (P = 0.4231), between the APRI and LS (P = 0.4621), or between the HCV viral load and LS (P = 0.8104).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0190455.g002