Connective tissue growth factor dependent collagen gene expression induced by MAS agonist AR234960 in human cardiac fibroblasts
Table 1
The abbreviations used for non-failing hearts are as follows: F, female; M, male; W, white; EF, left ventricular ejection fraction measured prior to explant; CVA, cerebrovascular accident; GSW, gunshot wound. Drug therapy acute indicates treatment in the emergency room or intensive care unit prior to brain death: Drugs: DOB, dobutamine (n = 2); DOP, dopamine (n = 4); EPI, epinephrine (n = 1); NE, norepinephrine (n = 4); THY, thyroxine (n = 4), other, nimodipine, phenylephrine, vasopressin, atropine (n = 1 or 3). Drug therapy chronic, indicates drugs (phenobarbital, coumadin, spironolactone, synthroid) taken by patients prior to admission, as reported by family members (n = 1). The abbreviations used for failing hearts are as follows: F, female; M, male; W, white; B, black; NatAm, Native American; A, asian; O, other; EF, left ventricular ejection fraction measured prior to explant; DCM, dilated cardiomyopathy (pre-transplant diagnosis); ICM, ischemic cardiomyopathy; VCM, valvular cardiomyopathy. Drug therapy lists as follows: AM, amiodarone (n = 13); CAPT, captopril (n = 4); CARV, carvedilol (n = 8); DIG, digoxin (n = 10); DOB, dobutamine (n = 6); EN, enalapril (n = 1); LIS, lisinopril (n = 7); MET, metoprolol (n = 7); MIL, milrinone (n = 10); dofetilide, losartan, mexiletine, fosinopril, trazodone, colchicine (n = 1 or 2).