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A logic-based dynamic modeling approach to explicate the evolution of the central dogma of molecular biology

Table 5

The attractors of the Boolean model depicted in Fig 1C obtained from the synchronous update method.

In each version of the model, demonstrated are the number of single SSs, SSs with multiple states (limit cycles) and corresponding normalized basin of attractions. The color gradient from red, yellow to green illustrate the lowest to highest values. The attractors A to I are encoded in the following order: Activator/DegProtein/DegRNA/DNA/miRNA/mRNA/Protein.

Table 5

doi: https://doi.org/10.1371/journal.pone.0189922.t005