N-acetylcysteine (NAC) ameliorates Epstein-Barr virus latent membrane protein 1 induced chronic inflammation
Fig 4
NAC treatment reduces the quantifiable levels of chronic inflammation in the L2LMP1 transgenic mice.
Top: typical epifluorescent image taken 24 hours after IV injection of p680 into a transgenic L2LMP1 mouse at phenotypic stage 5 (St5) and negative sibling control (NSC); colour scale shows radiant efficiency range displayed ((photons/sec/cm2/sr)/(μW/cm2)). Below: graphs depicting the mean (with SD error bars) radiant efficiency (Y axis) observed in mice in increasing age groups (X axis) imaged at 24 and 30 hours (as indicated) post injection of 1nmol/mouse p680. Four groups were examined, transgenic (Tg) and NSC mice, either untreated or treated with NAC-water. N = 2 to N = 8 for each age and group (as detailed in Table A in S2 File).