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Porcine brain extract promotes osteogenic differentiation of bone marrow derived mesenchymal stem cells and bone consolidation in a rat distraction osteogenesis model

Fig 3

PBE treatment improved the quality of new callus as shown by μCT analysis and mechanical test.

(a) 3D μCT images of the tibia distraction zone in the two groups at week 3 and 6. (b) The value of BV/TV at week 3 and 6. (c) Mechanical properties (including E-modulus, ultimate load, and energy to failure) of distraction regenerates. *p < 0.05, compared to the PBS group, n = 4 at week 3; and n = 6 at week 6.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0187362.g003