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In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels

Fig 7

Effect of DAQ-DcpSi on luciferase activity driven by either the SMN2 promoter and SMN splicing cassette (filled triangles) or CMV promoter (open triangles).

All data shown as mean ± range of duplicate determinations for a representative experiment of two performed which gave very similar results. Where not shown, error bars are within the size of the symbols.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0185079.g007