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In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels

Fig 4

Effect of RG3039 on SMN transcripts.

HEK-293T cells were treated with the indicated concentrations of RG3039 for various periods of time (4, 8 or 24hr) before the levels of SMN transcripts were measured using ddPCR. All data shown as mean ± s.e.m. and where not shown error bars are within the size of the symbols.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0185079.g004