Docking-based modeling of protein-protein interfaces for extensive structural and functional characterization of missense mutations
Fig 6
Effect of nsSNPs in TNNC1 interaction network based on complex structures and modelled interactions.
Analysis of TNNC1 interaction network by combining structural data and docking models can identify different nsSNPs that could affect the interaction with different proteins. Protein-protein interactions with available structure are represented as red edges. Modelled interactions are represented as cyan edges. Selected protein-protein complex structures are shown, with residue color coding for the predicted NIP values as in Fig 5.