Glycoprotein YKL-40: A potential biomarker of disease activity in rheumatoid arthritis during intensive treatment with csDMARDs and infliximab. Evidence from the randomised controlled NEO-RACo trial
Fig 2
YKL-40 was associated with disease activity, IL-6 and MMP-3 in the DMARD-naïve RA patients.
The figure shows scatter plots of YKL-40 levels with disease activity measured as DAS28 (A), tender joint count (B), erythrocyte sedimentation rate (C), IL-6 (D), and MMP-3 (E) at the baseline. Correlation coefficients were calculated by the Spearman method. YKL-40 showed positive correlation to DAS28, tender joint count, ESR, IL-6 and MMP-3 at the baseline.