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Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others

Fig 6

Fluoro-thalidomide not thalidomide promotes VEGF induced tube formation in HUVECs.

(A) Representative photographs were shown in tube formation. Quantitative analysis of stained tube formation structures was measured by using angiogenesis imaging analyzer, version 2 in five different areas for each well. We measured joint (B), joints (B), paths (C), tube area (D), lengths (E). Data are shown as mean ± SEM (n = 3 or 4). ##, p < 0.01 vs. Control group, and *, p < 0.05 **, p < 0.01 vs. Vehicle-treated group.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0182152.g006