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Effect of inter-train interval on the induction of repetition suppression of motor-evoked potentials using transcranial magnetic stimulation

Fig 1

The stimulation protocol included eight sequences.

In the first seven sequences, 30 trains consisted of four or twenty pulses. The inter-train interval (ITI) was determined as an interval between the last pulse in a train and the first pulse in the next train. The ITIs were 3, 4, 6, 7, 12, and 17 s and an inter-stimulus interval (ISI) was 1 s. In the last sequence, 120 pulses were applied with an ISI of 1 s. When the last sequence was divided into 4-pulse trains, the ITI was equal to ISI and the number of trains was 30. The sequences were applied in a random order except the 120 pulses/train sequence which was always given last.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0181663.g001