Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster
Fig 2
Illustration of DNA methylation landscape across the sequenced region for European and African Americans.
Average DNA methylation levels for European Americans are denoted by blue circles and average DNA methylation for African Americans are shown as red circles. Highlighted regions correspond to the FADS1 promoter (green), putative enhancer (yellow) and FADS2 promoter (blue) regions. Dashed line represents 80% methylation. Triangle shaped points in the putative enhancer region are CpG sites that displayed significant ASM with rs174537 in the meta-analysis.