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Regulation of gut luminal serotonin by commensal microbiota in mice

Fig 2

Luminal and tissue 5-HT concentrations in the gastrointestinal tract of germ-free (GF) mice and GF mice reconstituted with SPF mouse feces.

(A) GF and EX-GF mice were sacrificed at 10 weeks of age. Luminal (n = 6–9) and (B) tissue (n = 6–8) 5-HT levels in GF (open circles) and EX-GF (closed circles) mice. *** P < 0.001 relative to the corresponding GF value.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0180745.g002