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Anti-inflammatory effects of ursodeoxycholic acid by lipopolysaccharide-stimulated inflammatory responses in RAW 264.7 macrophages

Fig 1

The molecular structure of ursodeoxycholic acid (UDCA) and the effect on the cell viability of RAW 264.7 macrophages.

(A) The molecular structure of UDCA. The macrophages were treated with various concentrations of UDCA (0, 0.5, 1, 2, or 5 mM) for 24 h. (B) Cell viability was measured using a CCK-8 assay and (C) a live/dead staining kit. Results are mean ± SD of triplicate experiments: **p < 0.01, significant difference as compared to the control and to each other.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0180673.g001