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Systems biology of the modified branched Entner-Doudoroff pathway in Sulfolobus solfataricus

Fig 8

Perturbation of the negative feedforward reaction of the npED branch.

Stochastic perturbations on the feedforward parameters affecting VGK. A) Pathway diagram of the npED branch with perturbation on the feedforward connection; B) Parametric plot relating Pyr and Gly with feedforward perturbations (red) and without feedforward perturbations (blue); C) Histogram of Pyr steady states with feedforward perturbations (red) and without feedforward perturbations (blue); D) Histogram of Gly steady states with feedforward perturbations (red) and without feedforward perturbations (blue).

Fig 8

doi: https://doi.org/10.1371/journal.pone.0180331.g008