Morphological analysis of human umbilical vein endothelial cells co-cultured with ovarian cancer cells in 3D: An oncogenic angiogenesis assay
Fig 7
Drug response comparisons between 3D mono-cultures and co-cultures.
(A) Dose-dependent responses comparing monocultures and co-culture, measured by cell viability inhibition percentages in a Matrigel sandwich treated with: (i) Cisplatin; (ii) Paclitaxel. (B) Tubule area reduction comparing monocultures and co-culture, after treatment by: (i) Cisplatin and (ii) Paclitaxel. *p<0.05 **p<0.01 compared with control using Student’s t-test.